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In Vivo CAR-T Hub

Explore In Vivo CAR-T Resources in One Convenient Hub White papers | Posters | Videos
Discovery
Antibody CMC
Plasmid DNA
RNA-tLNP
tLVV
Facility

Start Your In Vivo CAR-T Journey Now!

In vivo CAR-T is reshaping cell therapy by enabling direct immune cell engineering inside the patient, eliminating complex ex vivo steps such as

cell extraction, modification, and reinfusion. This streamlined approach improves speed, scalability, and cost efficiency. With flexible delivery

options, including RNA-LNP and viral vector technologies, in vivo CAR-T is opening a new path toward truly scalable cell therapies.

This resource hub brings together expert insights, technical content, and platform capabilities to support your in vivo CAR-T journey—from

discovery to delivery.

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In Vivo CAR-T Discovery

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Antibody CMC for In Vivo CAR-T

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Plasmid DNA for In Vivo CAR-T

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RNA-tLNP Delivery Pathway

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Targeted Lentiviral Vector (tLVV) DeliveryPathway

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Explore OurIn Vivo CAR-T Facility

In Vivo CAR-T Discovery

Build a strong foundation with optimized CAR design, antibody selection, and early-stage validation strategies.

What You’ll Learn

  • Strategies for CAR construct optimization
  • Antibody screening and lead identification
  • Key considerations for in vivo functionality

Learn About Our Services

Antibody CMC for In Vivo CAR-T

Ensure robust and scalable antibody fragment production with tailored CMC strategies for in vivo applications.

What You’ll Learn

  • Cell line development for antibody fragments
  • Upstream and downstream process optimization
  • Quality and consistency in biologics manufacturing

Learn About Our Services

Plasmid DNA for In Vivo CAR-T

High-quality plasmid DNA is critical for both viral and non-viral delivery pathways.

What You’ll Learn

  • Multiple linearized DNA options 
  • Critical quality attributes for plasmid design
  • Poly(A) sequence control and its impact on expression

Get Free Consultation

RNA-tLNP Delivery Pathway

Enable targeted, non-viral delivery of CAR constructs through advanced RNA-tLNP systems.

What You’ll Learn

  • mRNA & circRNA strategies in in vivo CAR-T
  • LNP formulation & conjugation strategies and CMC considerations
  • Transient expression and safety advantages

Learn About Our Services

Targeted Lentiviral Vector (tLVV) Delivery Pathway

Leverage targeted lentiviral vectors (tLVV) for efficient and durable in vivo gene delivery.

What You’ll Learn

  • Lentiviral vector design for in vivo targeting
  • Packaging system, producer cell line and scalability considerations 
  • Regulatory and safety perspectives

Get Free Consultation

Explore Our In Vivo CAR-T Facility

Why Choose Us for In Vivo CAR-T?

  • End-to-End Platform: Discovery to GMP manufacturing
  • Multi-Modal Expertise: Antibody, plasmid, RNA, LNP, and viral vector
  • Speed & Scalability: Designed for rapid clinical translation
  • Global CDMO Experience: Supporting innovative cell and gene therapies worldwide

Video

Facility Tour for In Vivo Applications