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Cell therapy and lentiviral vector LVV CDMO solutions

Cell Therapy Solutions

Cell therapies are transforming the treatment of cancer, autoimmune disorders, and genetic diseases. Yet challenges in CAR discovery, lentiviral vector manufacturing, scalability, and regulatory readiness can slow progress. ProBio's integrated Cell Therapy Solutions unite discovery, vector development, GMP manufacturing, and commercialization support to help accelerate programs from concept to market.

Successful cell therapy development requires seamless integration across discovery, vector development, manufacturing, and regulatory execution. ProBio unites these critical capabilities within a single platform, supporting programs from early-stage research through commercialization.

Through expertise in CAR lead discovery, plasmid and lentiviral vector development, GMP-compliant manufacturing, and regulatory support, we help innovators reduce complexity, mitigate risk, and accelerate the advancement of cell therapies with confidence.

In Vivo CAR-T Discovery

LVV Plasmid Services

LVV Packaging Test and Manufacturing

LVV Drug Product IND-Enabling CMC

LVV GMP Manufacturing

LVV Plasmid CMC to GMP

Proprietary Packaging Systems Delivering Stable and Scalable LVV Processes

Cell Therapy Solutions WorkflowPreclinical studies through CAR-T discovery, CMC, clinical development and BLA approval. PreclinicalStudiesCAR–TDiscoveryIND–EnablingCMCIND Filing/FDAApprovalEarly StageClinicalLate StageClinicalBLA Filing/FDAApproval Pro GradeCAR Lead Discovery& PharmacologyIND CMCClinical GMPGradeClinical GMPGradePC & PVGMP Grade
Proprietary packaging systems delivering stable and scalable LVV processes LVV packaging workflow using transfer and helper plasmids, PowerS-293T packaging cells, and producing lentiviral vector. Proprietary Packaging Systems Delivering Stable and Scalable LVV Processes TransferPlasmid GOI: Gene of Interest LentiBone™ Backbone for LVV Transfer Plasmid LentiHelper™VSV-GLentiHelper™RevLentiHelper™GagPol Ready to Use 3 LentiHelper™ Plasmids with FDA DMF Registration Licensed Adherent Cell Line PowerA™–293T with CDMO Authority Proprietary PowerS™–293T Suspension Cell Line with FDA DMF Registration Lentiviral Vector (LVV)

Accelerating Cell Therapies with ProBio

Discovery to commercialization cell therapy platform under one roof

Discovery-to-Commercialization Under One Roof

Connect every stage of cell therapy development through a single partner, from CAR lead discovery and plasmid development to lentiviral vector manufacturing, GMP production, and commercialization support.
Proprietary LentiBone and LentiHelper platforms for scalable LVV manufacturing

Proprietary Platforms for Scalable LVV Manufacturing

Accelerate development with proprietary LentiBone™ transfer plasmids, LentiHelper™ helper plasmids, and the PowerS™-293T suspension cell line, enabling scalable, high-yield lentiviral vector manufacturing with titers up to 1E8 TU/mL and recovery rates up to 60%.
Global GMP manufacturing and regulatory readiness for cell therapies

Global Manufacturing & Regulatory Readiness

Support clinical and commercial programs with GMP facilities in the US and China, robust supply chains, and expertise spanning IND-enabling development, GMP manufacturing, and BLA support.

Applications and Use Cases

Poly(A) control for plasmid and mRNA whitepaper cover

FLYER

GMP Viral Vector Manufacturing

Discover GMP LVV and AAV manufacturing solutions designed for rapid development, scale-up, and commercialization.
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ProSyn linearized DNA flyer cover

FLYER

LVV Packaging Test

Explore ProBio's LVV packaging test services and discover how they support candidate selection and CMC-enabling feasibility studies.
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GMP plasmid manufacturing flyer cover

WEBINAR

Targeted LVV Design for In Vivo CAR-T

Discover design strategies for targeted lentiviral vectors, producer cells, and T-cell-specific delivery.
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Frequently Asked Questions

Facing cell therapy development challenges?

Facing Cell Therapy Development Challenges?

Connect with our experts to discuss your development and manufacturing strategy.

Talk to Our Experts