Antibody Affinity Maturation Service
A platform enabling rapid, unbiased, and high-efficiency optimization of
antibody candidates, delivering superior affinity and developability by
combining AI/ML-aided design, precise full-coverage mutagenesis, and high-
throughput multi-parameter screening, whilst overcoming the limitations of
traditional library bias.
Accelerate Antibody Lead Optimization with Affinity Maturation
Affinity Improvement
A guaranteed ≥10-fold improvement enabling your projects to progress to clinical stages faster.
Targeted for Success
Our unbiased, oligo-based precise mutagenesis library (PML) improves screening efficiency.
Proven Experience
We provide rapid turnaround and proven execution (220+ projects) to reduce timelines and uncertainty.
Next-Generation Antibody Affinity Maturation Platform
Accelerate antibody lead optimization with precise mutagenesis and high-throughput screening. Achieve high-affinity candidates in weeks.
Deluxe Service Package
A two step screening approach to maximize hit rates and screening efficiency. Firstly, the PML is utilized to identify crucial hotspots. Secondly, a combinatorial mutagenesis library is constructed and used to identify the top 3-5 sequences.
• > 10-fold improvement
• 14 – 16 weeks
• 14 – 16 weeks
Standard Service Package
Precision trimer library construction with phage display screening to rapidly obtain high-affinity variants. Flexible customization of mutation types and proportions offered, delivering streamlined library construction.
• > 5-fold improvement
• 12 – 14 weeks
• 12 – 14 weeks
Case Study
Achieving >1,000× Improvement in Antibody Binding Affinity
Resources
WEBINAR
Antibody Engineering and Developability Service
This webinar covers integrated antibody engineering and developability assessment platforms by ProBio to expedite the drug discovery process.
HAND
BOOK
Antibody Lead Optimization Service
Learn more about how to accelerate antibody candidates with our lead optimization services.
POSTER
Achieving High Affinity by Affinity Maturation
Utilization of PML and HTP FASEBA screening platform for antibody affinity improvements.
HAND
BOOK
Discovery of Functional Antibody Leads at Early Stage of Lead Screening
Solutions to obtain more functional leads at an earlier stage2.
Frequently Asked Questions