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Pseudovirus Neutralization Assay Service

Pseudovirus Neutralization Assay (PNA) services and assay kits designed to evaluate the neutralizing activity of antibodies, sera, peptides, small molecules, and other therapeutic candidates against SARS-CoV-2 and its variants. 
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High-Sensitivity Pseudovirus Neutralization Assays for Antibody and Vaccine Evaluation

Integrated Service Package

A comprehensive one-stop solution featuring gene synthesis, virus packaging, target cell engineering and functional evaluation, to accelerate candidate evaluation.

High-Throughput, Cost-Effective Screening

Providing reliable and consistent results that correlate with live virus neutralization assays, reducing cost, complexity, and biosafety constraints.

Complete Neutralization Solutions

Providing both Pseudovirus Neutralization Assay Services and Kits, for neutralizing antibody testing, vaccine efficacy evaluation, and antiviral candidate screening.

Rapid Delivery in as Fast As 5 Weeks

Pseudovirus Neutralization Workflow
Pseudovirus Neutralization Workflow Six-step workflow from Proposal design through Plasmid preparation, Virus/vector packaging, Virus/vector purification, QC, and Pseudovirus Neutralization Assay, totaling 5 to 8 weeks. 2 – 4 Weeks 1 Week 0.5 Weeks 0.5 Weeks 1 – 2 Weeks Proposal Design Plasmid Preparation Virus / Vector Packaging Virus / Vector Purification(optional) QC PseudovirusNeutralization Assay 5-8 Weeks

Neutralization Assay

1 – 3 Weeks
  • Physiologically relevant viral entry model that closely replicates natural infection pathways.
  • Extensive Pseudovirus library, including SARS-CoV-2, SARS-CoV-1, Lassa fever, Nipah virus, and multiple variants.
  • Custom Pseudovirus development to support specialized research programs.
  • High-specificity screening for therapeutics that block viral entry.
  • High-sensitivity detection (S/N > 100) for clear differentiation between candidate activities.

Neutralization Kit

1 – 3 Weeks
  • Physiologically relevant viral entry model.
  • Broad variant coverage support for multiple sars-cov-2 variants.
  • High specificity for mechanism-based screening.
  • High-specificity screening for therapeutics that block viral entry.
  • High-sensitivity detection (S/N up to ~100) for clear differentiation between candidates.
  • Ready-to-use assay platform that reduces optimization time and accelerates study initiation.
  • Preserves sample integrity, particularly for valuable serum samples.

Case Study

Validating Pseudovirus Neutralization Assays for Rapid and Accurate Antiviral Candidate Screening.

Validating Pseudovirus Neutralization Assays for Rapid and Accurate Antiviral Candidate Screening.

Resources

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