Cell Line Engineering and Bioassay Service
Custom cell line generation, assay development, optimization, validation, and screening services to support biologics discovery and development. Our service is designed around a therapeutic's mechanism of action (MoA) helping you to evaluate biological activity, target engagement, potency, efficacy, and functional responses throughout development.
MoA-Driven Bioassay Development and Functional Cell Line Services
Comprehensive Platform
Cell-based bioassays specifically tailored to therapeutic mechanisms of action, to address complex MoA driven assay design, complemented by high-throughput screening capabilities using validated cell-based systems.
IND Filing Support
Our assays are designed and validated according to ICH and USP guidance and we provide traceability, documentation, and experimental records suitable for regulatory submissions.
Proven Expertise
We leverage our expertise in developing bioassay methods for over 100 targets, including monoclonal antibodies, bispecific antibodies and cytokines. Our optimized, sensitive, and reliable bioassay systems, directly address data quality and reproducibility issues.
Cell Line Engineering in as Fast as 8 Weeks
End-to-End Engineered Cell Line and Bioassay Development
MoA Tailored Functional Assays
Cell-based bioassays tailored to therapeutic mechanisms of action.
- Immune checkpoint drug screening
- Cytokine pathway study
- GPCR drug screening
- ADCC/ADCP bioassay
- Cell-based binding screening
- In vivo tumor models
- Reporter-labeled cell lines
Comprehensive Cell Line Library
Customized functional and reporter cell lines for target-specific studies.
- 450+ CHO-K1 or HEK293 OE cell lines
- 100+ Pathway reporter cell lines
- 200+ GPCR reporter cell lines
- 15+ Cytokine response cell lines
- 10+ MC38/CT26 tumor model cell lines
- 200+ Human cancer cell lines
- 50+ Mouse & other animal cell lines
Case Studies
Enabling Rapid Functional Evaluation of Immune Checkpoint Therapies Through Engineered Reporter Cell Platforms.
Cell-Based Reporter Assays for Cytokine Pathway Analysis and Therapeutic Antibody Neutralization.
Accelerating Fc Effector Function Analysis Through Robust Cell-Based Bioassays.
Resources
BROCHURE
Biologics Discovery Services Brochure
Tailored discovery strategies for diverse biologics modalities, designed to enhance success rates.
FLYER
ADC Discovery Service
One-stop solution from target to preclinical candidates (PCC).
HAND
BOOK
How to Design and Evaluate Bispecific Antibodies (BsAbs)?
Develop bsAbs discovery strategies based on structure.
BROCHURE
In Vitro Pharmacology Solutions
Comprehensive bioassay offerings, helping smooth the journey from discovery to lead molecule.
Frequently Asked Questions