Host Cell Commercial License
Platform licensing of proprietary CHOK1 host cells and vectors.
CHO Host Cell Line Licensing for Biologics Manufacturing
Comprehensive Platform Package
- CHOK1-GenS & CHOK1-ADCC+ host cells
- Media system, protocols and technical support
- Supports different molecules (mAb, bsAb, protein)
Proven CHOK1 Performance
- mAb titer up to 8.72 g/L
- bsAb up to 5.56 g/L
- Protein up to 9.19 g/L
- 60-90 generation stability
Regulatory-Ready Platform
- FDA DMF available
- Supports IND/NDA /BLA filings
- Full traceability documentation package
IP Clear
- CHO-K1 ECACC license agreement
- Proprietary vectors available
A Delivery Package Designed for Complex Biologics
Host System
- CHOK1-GenS or CHOK1-ADCC+ (1 vial, 107cells/vial)
- Proprietary vector (50 μg)
- 200 bp for regions up- and down- stream of the restriction sites
Full Traceability Documentation
- ECACC license agreement and original invoice
- Adaptation report
- cGMP cell banking report
- cGMP cell bank testing report
- Vector synthesis report
- Vector map and key elements description
Detailed Protocols and Guidance
- Cell culture protocol
- Clone strategy to help construct plasmid correctly
- (enzyme cleavage used for gene of interest clone and plasmid linearization)
- Cell line development protocol to screen cell clone with the host cell and vector
- (including transfection, cell pool screening and cell clone screening)
Case Studies
High-Performance and Scalable Expression with the CHOK1‑GenS Platform.
Enhanced ADCC Activity and Potency with the CHOK1-ADCC+ Platform
Resources
HAND
BOOK
Cell Line Development Solutions for Biomanufacturing
Break through to next level of productivity with our integrated solutions.
WHITE
PAPER
Optimized Cell Line Development
Strategies for Bispecific Antibody Manufacturing.
HAND
BOOK
How to Design and Evaluate Bispecific Antibodies (BsAbs)?
Develop bsAbs discovery strategies based on structure.
POSTER
CHOK1-ADCC+
High-Performance Host Cell System for ADCC Biotherapeutics.
Frequently Asked Questions