Fast Gram-Scale Antibody Production
1 gram mAb delivered in 5 weeks, with integrated solution for IND-enabling CMC.
From DNA to Gram-Level Protein in 5 Weeks
Fast Delivery
- 1 gram mAb delivered in 5 weeks
High Titer
- mAb average titer 1.5g/L, up to 3.4 g/L
- bsAb average titer 0.8g/L, up to 1.5g/L
CHO-K1 Cell
- The same host cell used in CMC development
- One-stop solution from discovery to IND
Flexible Modalities
- Monoclonal (mAb), bispecific (bsAb), & multispecific antibodies
- Recombinant proteins
- Fusion proteins
Rapid Gram-Level Protein Production
Codon Optimization
Expression Plasmid Preparation
Fast Antibody Production
ProGram Fast
5-8weeks
- Determine CMC candidates
- Developability assessment
- Host cell: CHO1-GenS, CHO1-ADCC+
Electroporation
Case Studies
High Titer and Purity of Monoclonal Antibody. This case study demonstrates ProBio's ProGram Fast service delivering gram-scale mAb production from CHO-K1 cells.
High Titer and Purity of Asymmetric Bispecific Antibody. This case study showcases the same ProGram Fast platform applied to a more complex molecule.
Resources
HAND
BOOK
Cell Line Development Solutions for Biomanufacturing
Break through to next level of productivity with our integrated solutions.
WHITE
PAPER
Optimized Cell Line Development
Strategies for Bispecific Antibody Manufacturing.
HAND
BOOK
How to Design and Evaluate Bispecific Antibodies (BsAbs)?
Develop bsAbs discovery strategies based on structure.
POSTER
ProGram Fast
Gram Level Fast Sample Preparation, 1 Gram mAb Delivered in 5 weeks.
Frequently Asked Questions