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Assay cell lines are used in a variety of applications, including gene functional studies, binding/blocking screening assay, and cross-species binding screening assay during antibody development. ProBio has successfully delivered high-quality services to over 500 global customers. With expertise in developing more than 100 bioassay methods, we provide effective, sensitive, and reliable solutions that help our customers progress from early research to commercialized projects.
One-stop solution: Providing a comprehensive solution by developing cell-based bioassay methods rooted in the mechanism of action (MoA) and offering high-throughput screening services. Simply provide us with your gene of interest.
Expert analysis: Specializing in the development, optimization, and validation of biological activity analysis methods in accordance with ICH and USP guidelines.
Compliance assurance: Clear background and traceability of cell line, along with thorough experiment records to support IND filing.
Experienced team: Extensive expertise in developing bioassay methods for over 100 targets, including monoclonal antibodies, bispecific antibodies, cytokines, and more.
Please download the project evaluation form, fill it and send it to us for an evaluation.
Immune Checkpoint Reporter Bioassay Service
Part of developed cell-based bioassay methods
Cytokine Neutralization Service
GPCRs Bioassay Service
ADCC/CDC/ADCP Bioassay Service
ProBio addresses off-target effects in antibody development by utilizing specialized cell lines to identify distinct proteins, including isoforms. Our efficient cell-based binding screening enables the screening of specific antibodies for selective protein targeting.
In vivo pharmacology study
Reporter-labeled cell lines are invaluable research tools for studying in vivo tumor model imaging and in vitro CAR-T tumor-killing. ProBio has developed a range of reporter-labeled cell lines, utilizing widely employed luminescence and fluorescence reporter systems to facilitate drug evaluation.
Example: advantages of luciferase-labeled target cells to assess CAR-T killing