ProSyn™ Cell-Free Linearized DNA
Advanced cell-free production of GMP quality linearized DNA templates with proprietary primer pool.
Phase Appropriate Plasmid Preparation Support
Simple, Rapid Manufacturing
Eliminate cell‑banking steps and reduce overall processing time to less than half that of traditional E. coli fermentation.
Milligram-Level GMP Product Fast
Obtain the precise quantities you need for your projects, with the assurance of GMP quality and high accuracy.
Proprietary Platform
Our proprietary PowerStarry™ Primer Pool features a stable structure and broad universality, compatible with any restriction site and adaptable to diverse project needs.
From Plasmid to Batch Release in 11 Days
ProSyn™ Linearized DNA Platform
Template Plasmid
Rolling Circle Amplification
Enzyme Digestion
ProSyn™
Linearized DNA
Single strand for template plasmid
ProSyn™ Linearized DNA platform
Amplified DNA
Phi29 DNA polymerase
Monomer size
Endonuclease
Case Studies
ProSyn™ Platform Delivers High-Purity Linearized DNA with Rapid Amplification
Cell-Free Linearized DNA Delivers Comparable mRNA Performance to E. coli-Derived Templates
Resources
WHITE
PAPER
PAPER
Challenges and Solutions in the Poly(A) Control
Learn more about control strategies to ensure consistent poly(A) length and purity, from upstream plasmid synthesis to downstream production.
FLYER
Cell-Free Plasmid Linearization At Speed Through ProSyn™
Discover scalable, high purity linearized DNA with ProSyn™ platform, leveraging rolling circle amplification and an optimized cell-free enzymatic DNA synthesis platform.
FLYER
Linearized DNA Manufacturing
Read how linearized DNA manufacturing is optimized through various processes, from traditional E. coli fermentation-based to cell-free platforms.
FLYER
Manufacturing Plasmids for mRNA Vaccines
Learn about an integrated and accelerated one-stop CDMO solution for IND filing: design, manufacturing, and downstream application for mRNA vaccines.
Frequently Asked Questions