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Webinar – Reduce Risk in VHH and BsAb Discovery with Early Immunogenicity Assessment


sdAb Discovery & ExpressCMC™ with Cell Line Development Webinar

Accelerating VHH and bispecific antibody development is no longer just about speed, it’s about progressing the right candidates with confidence. Early insights into safety, immunogenicity, and developability are critical to reducing costly downstream risks and delays.

In this webinar, ProBio will showcase an integrated discovery strategy that combines single B-cell–based antibody discovery with advanced immunogenicity assessment. This approach enables rapid identification of high-quality candidates while providing early-stage insights to support smarter decision-making.

Time Topic
14:00-14:50 A single B cell-based novel approach to accelerate the discovery of VHH and bispecific antibody
  • Brief overview of current discovery strategy
  • Introduction of a novel single B cell based discovery approach
  • Case study with comparison between single B cell vs. phage display
14:50-15:20 De-risk of pre-clinical candidate by in silico and in vitro immunogenicity assessment
  • The origin and impact of immunogenicity
  • Current bottleneck of immunogenicity evaluation
  • ProBio’s one-stop solution of immunogenicity assessment

Speaker: Dr. Derek Chen, Sr. Director, Antibody Drug Discovery Dept., ProBio

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