Antibodies have emerged as significant therapeutics in the market. Accelerating antibody discovery is essential in the fight to develop first-in-class drugs or treatments for new pandemic pathogens, such as coronavirus. Fully human antibody discovery is widely used in early antibody leads discovery. In this webinar, we compare how scientists use innate immune systems to develop phage displayed libraries, Ab humanized animals, and single B cell technology. Recommended strategies for human antibody discovery will also be discussed.