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ProSpeed™ Single B Cell Antibody Discovery Service
TM
ProSpeed Single B Cell Antibody
Discovery Service
Better Sequence Diversity，More Functional Ab Binders
Faster Timeline，More Cost-effective
Challenges of Traditional Beacon-Based Single B Cell Antibody
Discovery Approach
Low on-chip screening capacity limits
the number of positive binders
recovered
Only “yes or no” binary readout for
on-chip screening. Difficulty in various
on-chip functional assay
Reduced success rate for multi-round(>3)
of on-chip screening
Limited assay sensitivity leading to false
negative/positive
ProBio’s Solution: Tackling Each Challenge at A Time
Immunization
Get Functional Antibody
Sequences in 1 month!
B cell Harvest and Enrichment
In-chip Screening Assays
(antigen specificity, cross-reactivity,
ligand blocking, affinity ranking )
Chip capacity upgrade from 11K to 20K,
~2× screening capacity
Early on-chip affinity ranking, avoid random
Export Single B cell
clone export
(Export desirable binders by Beacon affinity score)
Ab expression without costly gene synthesis
/plasmid preparation
ProSpeedTM Expression
Various & multi-round functional assay
Improved assay sensitivity
Binding/ Functional Screening Assays
(RGA/ Enzymatic/ internalization/
epitope binning, etc.)
Reduces >50% the cost and time of obtaining
functional Abs
Sequencing and Ab production
Available for Discovery of IgG and sdAb
mAb sdAb
ProBioCDMO.com
+1-732-885-9188
Accelerating Ideas. Delivering Impact.
Why Choose ProBio?
Multiple, sequential in-chip
screening completed in 1 day
2-3 weeks(ProSpeedTM
Forward functional screening for
the largest B cell pool possible
Minimal diversity loss
expression) vs 4-6 weeks
(plasmid-based expression)
High-throughput binder assays
using ProSpeedTM expression.
Avoid missing high-quality
leads!
EXPEDITED
TIMELINE
HIGH
DIVERSITY
20+
Since 2019
250+
Years of experience in
antibody drug discovery
introduced Beacon® platform
Delivery of ProSpeedTM single B
cell screening projects
More Case Studies
in our poster
430+
>80%
average number of
positive binders per project
sequencing success rate
Time-Limited Promotion: Free Beacon Chip Upgrade!
Terms & Conditions:
Place an order for the ProSpeedTM Single B Cell Antibody Discovery
Service and enjoy a FREE upgrade in the on-chip screening step
from the 11k Chip to the 20k Chip.
This limited-time offer is valid for orders placed by March 31, 2026.
Benefit:
Up to ~2× Screening Capacity
Increase the chance of obtaining desired sequences
Save an average of $6,000 per project
20k Chip
11k Chip
~20,000
~11,000
NanoPens per chip
NanoPens per chip