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Proprietary strain suitable for poly(A) plasmid
Plasmid poly(A) purity guarantee
Poly(A) tail plays an important role in maintaining stability and expression of mRNA in a typical biological process. The poly(A) tail in mRNA is directly transcribed from linearized DNA. Therefore, poly(A) control in plasmid is essential.
Poly(A) tail purity is important for the expression and stability of the mRNA to function in vivo. And it tends to decrease with the increase of the passaging generations. Lack of poly(A) purity control has impact on further manufacturing. ProBio’s proprietary PowerS™-PolyAssure strain is able to guarantee poly(A) purity.