RNA-tLNP One-Stop Solution

Flexible & Integrated Service: from Plasmid to RNA-tLNP

Offer Two RNA Structures: IVT-mRNA & IVT-circRNA

RNA-tLNP: LNP Surface Modification Efficiency > 95%

Antibody conjugated lipid nanoparticle (RNA-tLNP) is a newly developed deliver system that has the advantages of strong targeting and high efficacy. Recently, it has been widely used in in vivo CAR-T therapy. After encapsulation, T cell-specific antibodies are directly targeted to the LNP surface, simplifying the traditional in vitro process.

ProBio provides one-stop solution from plasmid, linearized DNA, IVT-mRNA/IVT-circRNA and antibody manufacturing, LNP encapsulation to final RNA-tLNP, saving time and cost and reducing transfer complex.

Contact us

RNA-tLNP Workflow

RNA-tLNP One-stop Solution

• Pro Mfg.
  • Preclinical stage
  • Flexible encapsulation scale:
    mg-g
  • 3 weeks fast turnaround time
  • Fill and finish (manual)
• IND-enabling CMC
  • Integrated solution
  • IVT-mRNA IND-enabling CMC
  • Antibody IND-enabling CMC
  • RNA-tLNP IND-enabling CMC
  
  
• GMP Mfg.
  • Early clinical stage
  • Flexible GMP encapsulation scale: mg-g
  • 4 weeks fast turnaround time
  • Fill and finish (automatic)

Related Service

• Plasmid manufacturing
• Linearized DNA manufacturing
• Plasmid IND-enabling CMC
• mRNA manufacturing
• mRNA IND-enabling CMC