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Antibody-Oligonucleotide Conjugates (AOCs) represent the next frontier in targeted therapeutics, combining the precision of antibodies with the gene-modulating power of oligonucleotides. Unlike conventional nucleic acid drugs limited to hepatic delivery, AOCs enable extrahepatic targeting and enhanced tissue penetration.
AOC CMC is challenging, requiring both antibody and oligonucleotide expertise. ProBio provides integrated end-to-end AOC CMC services covering antibody, oligonucleotide CMC, and conjugation CMC. We have established platform processes and dedicated analytical method to accelerate your AOC project from DNA to IND.
Solving AOC’s core CMC bottlenecks
Antibody know-how powering Fast AOC CMC
Single-point project management saves you time